22 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... Toxicology #Diagnosis #Management
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... Pulmonary edema, Shock ... Labs: Anion-Gap Metabolic ... Acidosis, Respiratory
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
deterioration Shock ... and metabolic acidosis ... acidosis with both ... and cardiogenic shock ... Toxicology #Diagnosis #Management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... depressed) • Renal: metabolic ... acidosis, oliguria ... Classification #diagnosis #management ... #Overview #criticalcare
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
Shock Overview ... depressed) • Renal: metabolic ... acidosis, oliguria ... Classification #diagnosis #management ... #Overview #criticalcare
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Cardiogenic & Septic Shock ... Inborn Errors of Metabolism ... Presents as AG acidosis ... Differential #Diagnosis #criticalcare
Weaning from the Ventilator - Algorithm
Setting up for extubation success
 • Decrease demand — correct metabolic
demand — correct metabolic ... acidosis, decrease ... Algorithm #Extubation #CriticalCare ... #Management
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
shock, cryptic ... shock. ... reaction • Endocrine/Metabolic ... types #diagnosis #management ... #criticalcare #
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
 • Type B Intercalated Cell - "B"
cells response to Metabolic ... Alkalosis and Metabolic ... Acidosis • Type ... Muner Mohamed @MunerMohamed1 ... Intercalated #cells #pathophysiology
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Diagnosis and Management ... infection SEPTIC SHOCK ... circulatory and cellular/metabolic ... Patients w/ septic shock ... #QSOFA #SIRS #criticalcare