42 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... presentation - Clinical ... acidosis including ... Toxicology #Diagnosis #Management
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... Pulmonary edema, Shock ... Labs: Anion-Gap Metabolic ... Acidosis, Respiratory
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... depressed) • Renal: metabolic ... acidosis, oliguria ... Classification #diagnosis #management ... #Overview #criticalcare
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
deterioration Shock ... and metabolic acidosis ... acidosis with both ... and cardiogenic shock ... Toxicology #Diagnosis #Management
Shock Overview
A state of tissue hypoxia due to decreased or dysregulated oxygen delivery or extraction, resulting
death Common Clinical ... depressed) • Renal: metabolic ... acidosis, oliguria ... Classification #diagnosis #management ... #Overview #criticalcare
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Cardiogenic & Septic Shock ... Inborn Errors of Metabolism ... Presents as AG acidosis ... Differential #Diagnosis #criticalcare
American College of Critical Care Medicine algorithm for time-sensitive, goal-directed stepwise management of hemodynamic support in
American College of Critical ... goal-directed stepwise management ... to next step if shock ... #CriticalCare # ... Pediatrics #Sepsis #Management
Weaning from the Ventilator - Algorithm
Setting up for extubation success
 • Decrease demand — correct metabolic
demand — correct metabolic ... acidosis, decrease ... Algorithm #Extubation #CriticalCare ... #Management
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
impairment of cellular metabolism ... sweat) - its metabolism ... of lactate as a clinical ... a multitude of clinical ... the appropriate clinical
Pulmonary Embolism - Risk Stratification and Prognostication based on scores and clinical features

 • Bova score
on scores and clinical ... Transient Hypotension, Shock ... prognostication #diagnosis #management ... stratification #criticalcare