24 results
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... Acidosis (HAGMA ... with short bowel syndrome ... Aspirin - salicylate ... #Acidosis #HAGMA
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... acidosis including ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Salicylate metabolism.
#Pathophysiology #Metabolism #Toxicology #Salicylate #Aspirin
Salicylate metabolism ... #Pathophysiology ... #Metabolism #Toxicology ... #Salicylate #Aspirin
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... Acidosis, Respiratory ... #Salicylate #Aspirin ... #Toxicity #Toxicology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acidosis ↑ ↑ ... Acidosis <0.4 ... Metabolic acidosis ... D-lactate (short bowel syndrome ... M Methanol A Aspirin
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... • Incr Glucose Metabolism ... - Metabolic ... Acidosis • Shift ... #diagnosis #pathophysiology
Salicylate Toxicity - Diagnosis and Management

Clinical Findings
Pathophysiology
Workup
Treatment

By Stacy Marshall, MD

#Salicylate #Toxicity #Diagnosis #Management #Toxicology #Aspirin #Treatment
Diagnosis and Management ... Clinical Findings Pathophysiology ... Toxicity #Diagnosis #Management ... #Toxicology #Aspirin
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
acidosis (12-48 ... - Anion gap metabolic ... acidosis with both ... Poisoning #Toxicity #Toxicology ... #Diagnosis #Management
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
bodies are a normal metabolic ... by an anion gap acidosis ... fatty acid (FA) metabolism ... of re-feeding syndrome ... differential #diagnosis #management
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Hyperlactatemia • Metabolic ... acidosis • Rhabdomyolysis ... PRIS #Diagnosis #Management ... Pharmacology #Toxicity #Toxicology