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diagnosis toxicity management signs iron aniongap aspirin bulimianervosa causes colchicine complications differential ferrous heat heatstroke illness lacticacidosis mala metformin nejm
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... also includes symptoms ... of metabolic acidosis ... LacticAcidosis #Toxicity #Toxicology
Colchicine Toxicity Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly] 2-24 hrs • Severe GI distress
Renal failure • Metabolic ... acidosis • ARDS ... Colchicine #Toxicity #Toxicology ... #Symptoms #Signs
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
show anion-gap metabolic ... acidosis 4) Presentation ... ingestion/exposure Symptoms ... Acidosis, Respiratory ... Aspirin #Toxicity #Toxicology
Acute Iron Poisoning There are five classically described phases of toxicity: Gastrointestinal phase (~6 hours post-ingestion) -
post-ingestion) - Symptom ... acidosis (12-48 ... - Anion gap metabolic ... acidosis with both ... Poisoning #Toxicity #Toxicology
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
• Incr Glucose Metabolism ... Syndrome - Metabolic ... Acidosis • Shift ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Stages of Iron Toxicity Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
cause an anion gap metabolic ... Recovery from GI symptoms ... Ill Shock and metabolic ... acidosis • Metabolic ... Iron #Toxicity #Toxicology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
• Labs: - Metabolic ... acidosis - Rhabdomyolysis ... Collapse: • Pathophysiology ... Syncope • Signs/Symptoms ... - Mild lactic acidosis
Metabolic Pathways of Toxic Alcohols Panel A shows the metabolic pathways of toxic alcohols. Alcohol dehydrogenase
Metabolic Pathways ... Panel A shows the metabolic ... high anion-gap acidosis ... #Pathophysiology ... #Toxicology #ToxicAlcohols
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
Vomiting may lead to metabolic ... abuse may lead to metabolic ... acidosis (loss ... Complications #pathophysiology ... diagnosis #signs #symptoms
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