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diagnosis management differential signs syndrome algorithm causes hypokalemia pituitary psychiatry refeeding 21hydroxylasedeficiency 21ohd aflp anorexianervosa bulimianervosa cells chloride ckd diabetes
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... also includes symptoms ... of metabolic acidosis
Complications of CKD - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
Complications of ... imbalances or endocrine/metabolic ... #Pathophysiology ... #Nephrology #CKD ... #Complications
Euglycemic Diabetic Ketoacidosis (EuDKA) SGLT2 Inhibitors Increasing Indications Significant Adverse Drug Effects Definition of EuDKA • Metabolic acidosis with pH
Definition of EuDKA • Metabolic ... acidosis with pH ... level < 200 mg/dL Pathophysiology ... diagnosis #management #endocrinology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... postpartum): • Initial symptoms ... Monitor and Treat Complications
Refeeding Syndrome: Pathogenesis and clinical findings Patients at Risk of Refeeding Syndrome: - Little or no nutritional
• Incr Glucose Metabolism ... Syndrome - Metabolic ... Acidosis • Shift ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
life threatening complications ... Pressure: - Metabolic ... Hippurate - Metabolic ... acidosis: Proximal ... differential #potassium #nephrology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W
Excessive vomiting - Metabolic ... increase may cause metabolic ... acidosis - Cl ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
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