28 results
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... Acidosis (HAGMA ... Aspirin - salicylate toxicity ... causes lactic & ... #Acidosis #HAGMA
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... no respiratory cause ... show anion-gap metabolic ... acidosis 4) Presentation ... diagnosis #management #Treatment
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... Amyl nitrite - causes ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... LacticAcidosis #Toxicity
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
Abdominal pain, nausea ... deterioration Shock and metabolic ... acidosis (12-48 ... - Anion gap metabolic ... acidosis with both
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Elevation, Lactic Acidosis ... impairment of cellular metabolism ... sweat) - its metabolism ... perfusion - shock->treatments ... before beginning treatment
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
intoxication Cause ... Excessive vomiting - Metabolic ... metabolic acidosis ... metabolic alkalosis ... Diagnosis #Algorithm #Pathophysiology
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... Iron overdose can cause ... an anion gap metabolic ... acidosisMetabolic ... #Stages #Iron #Toxicity
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
 • Type B Intercalated Cell - "B"
cells response to Metabolic ... Alkalosis and Metabolic ... Acidosis • Type ... Muner Mohamed @MunerMohamed1 ... Intercalated #cells #pathophysiology
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
significant anion gap metabolic ... acidosis and ketonemia ... production, the rate of metabolism ... Treatment with IV ... and acidosis has