11 results
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... deterioration Shock and metabolic ... acidosis (12-48 ... - Anion gap metabolic ... acidosis with both
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... LacticAcidosis #Toxicity
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... show anion-gap metabolic ... acidosis 4) Presentation ... Acidosis, Respiratory ... diagnosis #management #Treatment
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... cause an anion gap metabolic ... Ill Shock and metabolic ... acidosisMetabolic ... #Toxicity #Toxicology
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
 • Type B Intercalated Cell - "B"
cells response to Metabolic ... Alkalosis and Metabolic ... Acidosis • Type ... Muner Mohamed @MunerMohamed1 ... Intercalated #cells #pathophysiology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... Ketosis (SK), acidosis ... The metabolism of ... algorithm #management #treatment ... #criticalcare #foamed
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
inevitably leads to Metabolic ... Acidosis. ... Metabolic Acidosis ... #foamed #criticalcare ... management #diagnosis #treatment
Methotrexate Renal Toxicity 
Prevention:
 • Alkalinize the urine, keep urine ph >7
 • Start pre-treatment 12
Methotrexate Renal Toxicity ... • Start pre-treatment ... fluids till you see metabolic ... alkalosis • Forced ... Methotrexate #Renal #Toxicity
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
❹ Call for MH treatment ... COMPLICATIONS AND OUTLINE TREATMENTS ... amiodarone/metoprolol Metabolic ... acidosis: hyperventilate ... Myoglobinaemia: forced
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Medication/Drug toxicity ... , Metabolic disturbance ... epilepticus Treatment ... underlying cause • Treatment