14 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... LacticAcidosis #Toxicity
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... show anion-gap metabolic ... acidosis 4) Presentation ... Acidosis, Respiratory ... diagnosis #management #Treatment
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
 • Type B Intercalated Cell - "B"
cells response to Metabolic ... Alkalosis and Metabolic ... Acidosis • Type ... Muner Mohamed @MunerMohamed1 ... Intercalated #cells #pathophysiology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... following first-pass metabolism ... - Metabolism - ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... Ketosis (SK), acidosis ... The metabolism of ... algorithm #management #treatment ... #criticalcare #foamed
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Hyperlactatemia • Metabolic ... acidosis • Rhabdomyolysis ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
Acidosis. ... Metabolic Acidosis ... #foamed #criticalcare ... management #diagnosis #treatment ... #pharmacology #
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Hemolysis, DIC Metabolic ... : Metabolic acidosis ... #Colchicine #Toxicity ... Toxicology #Phases #Pharmacology
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Toxicology Acute toxicity ... alkalosis and metabolic ... acidosis. ... Chronic toxicity ... #Toxicology #Pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
syndrome (PRIS) - acidosis ... glycol (solvent) toxicity ... result in lactic acidosis ... Versed) - CYP3A4 metabolism ... No pharmacologic