70 results
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... Acidosis (HAGMA ... during hypoxic metabolism ... Aspirin - salicylate toxicity ... #Acidosis #HAGMA
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... LacticAcidosis #Toxicity
Colchicine Toxicity 
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs 
 • Severe GI distress
Colchicine Toxicity ... Renal failure • Metabolic ... acidosis • ARDS ... #Colchicine #Toxicity ... Toxicology #Symptoms #Signs
Clinical presentation of metabolic or respiratory acidosis.

#acidosis #metabolic #respiratory #picture #diagram #signs #symptoms #presentation #Diagnosis
presentation of metabolic ... or respiratory acidosis ... #acidosis #metabolic ... picture #diagram #signs
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Ethylene Glycol Toxicity ... #Pathophysiology ... EthyleneGlycol #Metabolism
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... show anion-gap metabolic ... acidosis 4) Presentation ... Acidosis, Respiratory ... diagnosis #management #Treatment
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... Treatment: 1 ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology ... #Management #Treatment
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... deterioration Shock and metabolic ... acidosis (12-48 ... - Anion gap metabolic ... acidosis with both
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
• Incr Glucose Metabolism ... Syndrome - Metabolic ... Acidosis • Shift ... Syndrome #diagnosis #pathophysiology ... #symptoms #signs
Toluene Poisoning - Diagnosis and Management Summary
What is it?  Volatile hydrocarbon, Glue or paint-sniffing, Occupational
lipid-soluble, Toxicity ... Early raised AG acidosis ... normal anion gap acidosis ... may be ↑ or ↓ Treatment ... Diagnosis #Management #Treatment