21 results
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
High Anion Gap Metabolic ... Acidosis (HAGMA ... with short bowel syndrome ... Aspirin - salicylate toxicity ... #Acidosis #HAGMA
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Associated Lactic Acidosis ... (MALA) Pathophysiology ... use in cellular metabolism ... acidosis including ... LacticAcidosis #Toxicity
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... show anion-gap metabolic ... acidosis 4) Presentation ... Acidosis, Respiratory ... diagnosis #management #Treatment
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... • Incr Glucose Metabolism ... - Metabolic ... Acidosis • Shift ... #diagnosis #pathophysiology
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Hyperlactatemia • Metabolic ... acidosis • Rhabdomyolysis ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Respiratory Distress Syndrome ... : Metabolic acidosis ... #Colchicine #Toxicity ... Toxicology #Phases #Pharmacology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... following first-pass metabolism ... - Metabolism - ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
iniury, Compartment syndrome ... , Heat stroke, Metabolic ... Neuroleptic malignant syndrome ... Dermatomyositis) AKI - Pathophysiology ... oxidative iniury Treatment
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Etiology: • Pathophysiology ... Medication/Drug toxicity ... , Metabolic disturbance ... epilepticus Treatment ... underlying cause • Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
impairment of cellular metabolism ... sweat) - its metabolism ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome