pathophysiology metabolism causes neurology syndrome signs metabolic symptoms toxicology toxicity

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27 results

High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline

High Anion Gap Metabolic ... during hypoxic metabolism ... with short bowel syndrome ... causes lactic & ... #Anion #Gap #Metabolic

Colchicine Toxicity
Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly]
2-24 hrs
• Severe GI distress

Colchicine Toxicity ... Renal failure • Metabolic ... #Colchicine #Toxicity ... #Toxicology #Symptoms ... #Signs #Diagnosis

Metformin Associated Lactic Acidosis (MALA)

Pathophysiology of MALA
- Metformin interferes with the activity of the

Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... also includes symptoms ... of metabolic acidosis

Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with

Salicylate Toxicity ... show anion-gap metabolic ... ingestion/exposure Symptoms ... Labs: Anion-Gap Metabolic ... #Toxicology #diagnosis

Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
- Little or no nutritional

Refeeding Syndrome ... • Incr Glucose Metabolism ... - Metabolic ... #diagnosis #pathophysiology ... #symptoms #signs

Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
-

Abdominal pain, nausea ... post-ingestion) - Symptom ... deterioration Shock and metabolic ... - Anion gap metabolic ... #Toxicology #Diagnosis

Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:

$Hypochloremia - Differential Diagnosis Algorithm Cause - Decreased Intake: • Low salt in diet • Exclusive D5W$

Excessive vomiting - Metabolic ... - Gitelman SIGNS ... metabolic acidosis ... metabolic alkalosis ... Diagnosis #Algorithm #Pathophysiology

Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant

effect on negative symptoms ... following first-pass metabolism ... - Metabolism - ... Clozapine is known to cause ... #Toxicity #Diagnosis

Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead

an anion gap metabolic ... Recovery from GI symptoms ... Ill Shock and metabolic ... acidosis • Metabolic ... #Toxicology #Diagnosis

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