18 results
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
and Management ... Hypogonad (50%) • Metabolic ... malignancy Pathophysiology ... #Endocrinology ... #Treatment #Pathophysiology
Diuresis in Critical Care - Achieving a Negative Fluid Balance
Advantages Of A Negative Fluid Balance:
 •
Diuresis in Critical ... , address diuretic ... a contraction metabolic ... Early nephrologv ... Fluid #Balance #management
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
- Giantism or acromegaly ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Diuretics and Agents ... resistance • Metabolic ... irrigation • Management ... hyponatremia #Diuretics ... #Nephrology #Pharmacology
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... females Guillain-Barre ... Pathophysiology ... Syndrome #diagnosis #management ... #treatment #neurology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Excessive vomiting - Metabolic ... RENAL LOSS: - Diuresis ... increase may cause metabolic ... Diagnosis #Algorithm #Pathophysiology ... #Nephrology #Chloride
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
classes, including a diuretic ... hypokalemia and metabolic ... Vasculitis • Endocrinologic ... Cushing's syndrome, Acromegaly ... , and Guillain-Barre
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... the underlying pathophysiology ... GBS #Guillain #Barre ... Syndrome #diagnosis #management ... #neurology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 • Metabolic acidosis with pH
Definition of EuDKA • Metabolic ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
lost via osmotic diuresis ... Due to neuronal metabolism ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology