15 results
Pathogenesis and Pathophysiology of Diabetic Ketoacidosis (DKA)

DKA is a result of an absolute or relative insulin
of Diabetic Ketoacidosis ... of carbohydrate metabolism ... state and fat metabolism ... #DKA #Diabetes ... #Endocrinology
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS)
Absolute Insulin deficit:
 - Type I DM:
Pathophysiology ... (DKA) and Hyperglycemic ... Hyperosmolar Syndrome ... Polydipsia #dka ... #comparison #endocrinology
Comparison of Pathologic Breathing Patterns
Biot's respiration aka ataxic respiration:
 - Periodic breathing: hyperpnea (or normopnea) and
Biot's respiration aka ... breathing: - Metabolic ... acidosis (Diabetes ... (U) L = Lactic ... acid/Lactic acidosis
High Anion Gap Metabolic Acidosis (HAGMA) - Differential Diagnosis - GOLDMARK

Glycols - ethylene and propylene glycol
Oxoproline
Acidosis (HAGMA ... with short bowel syndrome ... toxicity causes lactic ... Ketoacidosis - diabetic ... #Acidosis #HAGMA
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
bodies are a normal metabolic ... by an anion gap acidosis ... of re-feeding syndrome ... • Diabetic ketoacidosis ... diagnosis #management #endocrinology
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Lactic Acidosis ... Acidosis: Inadequate ... underlying disease: Diabetic ... failure, Short bowel syndrome ... inborn errors of metabolism
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Lactic Acidosis ... Ischemia, Compartment Syndrome ... Inborn Errors of Metabolism ... Leukemia/Lymphoma), Diabetes ... Mellitus +/- DKA
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
diuretic use, Bartter syndrome ... , Gitelman syndrome ... acidosis: Chronic ... acidosis: Diabetic ... ketoacidosis, D-lactic
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
diuretic use, Bartter syndrome ... , Gitelman syndrome ... acidosisDiabetic ... ketoacidosis • D-lactic ... acidosis due to
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Due to neuronal metabolism ... #pathophysiology ... #endocrinology ... #diabetes