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diagnosis hematology management syndrome aflp algorithm anemia apml bandemia causes cbc classification coagulation differentiation disseminated fatty hemolytic hepatopulmonary hodgkins intravascular
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
free fatty acid metabolism ... rapidly develops (DIC ... , ascites, jaundice ... infiltration) Differential ... Liver #Pregnancy #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... or venipuncture sites ... + Bleeding Treatment ... diagnosis #causes #treatment ... #management #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... defects, Glutathione metabolism ... thrombocytopenia - DIC ... , TTP, HELLP, HUS ... Algorithm #workup #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... initiation • Differential ... Renal Failure Treatment ... #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Cell population has ... ingestions • Metabolic ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Hepatopulmonary Syndrome - Illness Script HPS is a pulmonary disorder of chronic liver disease characterized by a
abnormalities PATHOPHYSIOLOGY ... • Stigmata of cirrhosis ... : jaundice, ascites ... the left heart TREATMENT ... #diagnosis #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
persons • It has ... platelets - WBC ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #oncology #management
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