39 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic ... Toxicology #Diagnosis #Management
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
constellation of metabolic ... intracellular ions and metabolic ... acutekidneyinjury #Pathophysiology ... Presentation #TLS #Workup
Complications of CKD
 - Patients with stages 1-3 ([GFR] >30 mL/min) of CKD are generally asymptomatic;
imbalances or endocrine/metabolic ... #Pathophysiology ... #Nephrology #CKD
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Metabolic alkalosis ... Diagnosis #Causes #Workup ... #Nephrology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... free fatty acid metabolism ... Intermediate fatty acid metabolism ... obgyn #diagnosis #management ... #pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... → Hypokalemia Metabolic ... Gitelman #Syndrome #Pathophysiology ... #nephrology #diagnosis
Weaning from the Ventilator - Algorithm
Setting up for extubation success
 • Decrease demand — correct metabolic
demand — correct metabolic ... Algorithm #Extubation #CriticalCare ... #Management
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup

NAGMA
- Chem, ABG or VBG
- Calculate Anion
Framework and Workup ... NonAnionGap #Acidosis #Metabolic ... Differential #Diagnosis #Workup ... #nephrology
Intercalated cells response to Metabolic Alkalosis and Metabolic Acidosis
 • Type B Intercalated Cell - "B"
cells response to Metabolic ... Alkalosis and Metabolic ... Intercalated #cells #pathophysiology ... #nephrology
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... ICH Management ... • Increased metabolic ... #neurology #neurosurgery ... #management