21 results
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
dissipation of metabolic ... maintained fever CAUSES ... hyperthermia crisis (late sign ... Phaeochromocytoma Neurologic ... Anesthesiology #Anesthesia
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Phenylephrine - Anesthesia Pharmacology
Trade Name: Phenylephrine
Brand Name(s): Neo-Synephrine
Drug Type: α-1 Agonist
Time of Onset: Rapid
Duration of Action:
Phenylephrine - Anesthesia ... Pharmacology Trade ... Action: Hepatic metabolism ... NeoSynephrine #Anesthesia ... #Pharmacology
Generalized Seizures and Pseudoseizures
Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
by a toxic or metabolic ... Toxic and metabolic ... causes include ... Classification #Diagnosis #Neurology ... #Signs #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Causes of Fatigue ... Insufficiency Metabolic ... Pulmonary Disease Neurologic ... Myasthenia Gravis Pharmacologic ... Diagnosis #Algorithm #causes
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... hypokalemia and metabolic ... renal bruit or signs ... Vasculitis • Endocrinologic ... Neurologic disorders
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
in Anaesthesia ... rise is a late sign ... other, more common causes ... amiodarone/metoprolol Metabolic ... Anesthesiology #Anesthesia
Intracranial Hemorrhage (ICH) and Increased Intracranial Pressure (ICP) - Pathophysiology
ICH Management:
1. Manage Blood Pressure
  •
Pressure (ICP) - Pathophysiology ... = dilated BV = raises ... • Increased metabolic ... Pressure #ICP #Pathophysiology ... #neurology #neurosurgery