24 results
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... dissipation of metabolic ... maintained fever CAUSES ... hyperthermia crisis (late sign ... Anesthesiology #Anesthesia
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Phenylephrine - Anesthesia Pharmacology
Trade Name: Phenylephrine
Brand Name(s): Neo-Synephrine
Drug Type: α-1 Agonist
Time of Onset: Rapid
Duration of Action:
Phenylephrine - Anesthesia ... Pharmacology Trade ... Action: Hepatic metabolism ... NeoSynephrine #Anesthesia ... #Pharmacology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
rise is a late sign ... ❹ Call for MH treatment ... COMPLICATIONS AND OUTLINE TREATMENTS ... amiodarone/metoprolol Metabolic ... Anesthesiology #Anesthesia
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
out of cells may cause ... Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
Panhypopituitarism Treatment ... CHF) • Inborn Metabolism ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
DKA DIAGNOSTIC CRITERIA:
1. Serum glucose >250 mg/dL
2. Arterial pH <7.3
3. Serum bicarbonate <18 mEq/L
4. At least
to 30% of DKA cases ... significant anion gap metabolic ... Common, early signs ... production, the rate of metabolism ... Treatment with IV
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... following first-pass metabolism ... - Metabolism - ... Clozapine is known to cause ... Toxicity #Diagnosis #Pharmacology
Refeeding Syndrome Overview

What Is It?
	• Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
Electrolyte/fluid shifts caused ... from hormonal and metabolic ... changes and may cause ... hyperparathyroidism Treatment ... Differential #Diagnosis #Pathophysiology