78 results
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Glycol Toxicity #Pathophysiology ... #Toxicology #EthyleneGlycol ... #Metabolism #Fomepizole
Toxic Alcohol Ingestion
Alcoholic ketoacidosis - Methanol - Ethylene glycol - Isopropyl Alcohol
 • Metabolic Acidosis
 •
Toxic Alcohol Ingestion ... Isopropyl Alcohol • Metabolic ... edgarvlermamd #Alcohol #Ingestion ... #diagnosis #toxicology ... #comparison #table
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... via anaerobic metabolism ... includes symptoms of metabolic ... LacticAcidosis #Toxicity #Toxicology
Anion Gap Metabolic Acidosis
 • Diabetic Ketoacidosis ± Hyperglycemia ± Hyperosmolar
 • Alcoholic Ketoacidosis ± Hyperglycemia
Anion Gap Metabolic ... limb ischemia • Ingestion ... acidosis - Drugs ... 3rEtbK8 #AnionGap #Metabolic
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC Pharmacology ... Bioavailability - Metabolism ... Warfarin #DOAC #Pharmacology ... #NOAC #comparison
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism
Causes of Provoked Pediatric Seizures - Differential Diagnosis Algorithm - "DIMS" Mnemonic
Drugs:
 • Drug overdose
 •
DIMS" Mnemonic Drugs ... : • Drug overdose ... • Poisoning Infection ... Encephalitis Metabolic
Salicylate metabolism.
#Pathophysiology #Metabolism #Toxicology #Salicylate #Aspirin
Salicylate metabolism ... #Pathophysiology ... #Metabolism #Toxicology
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome Drug ... Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... Serotonin #Syndrome #Pharmacology ... differential #diagnosis #drug
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
(~6 hours post-ingestion ... -24 hours post-ingestion ... deterioration Shock and metabolic ... - Anion gap metabolic ... Poisoning #Toxicity #Toxicology