18 results
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
of congenital adrenal ... comparison #treatment #Peds ... #Endocrinology ... #Adrenal #pathophysiology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology
Primary AI = adrenal glands themselves are the problem. This
Insufficiency - ... Pathophysiology ... #Insufficiency ... #Pathophysiology ... #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD ... #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Insufficiency Addison's ... Insufficiency: ... Primary ovarian insufficiency ... #insufficiency ... addisons #disease #endocrinology
Congenital Adrenal Hyperplasia - 21-Hydroxylase Deficiency - Signs and Symptoms
 • Brain: Androgenization effects, Glucocorticoid effects,
Congenital Adrenal ... Deficiency - Signs and Symptoms ... pressure • Glucose Metabolism ... Deficiency #Signs #Symptoms ... #diagnosis #endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Adrenal Insufficiency ... Summary Primary Adrenal ... Insufficiency: ... ketoconazole, etomidate) Symptoms ... Diagnosis #Management #Endocrinology
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
hypothyroidism Pathophysiology ... mitochondrial oxidative metabolism ... Hypothyroid #Myopathy #pathophysiology ... #signs #symptoms ... #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... thickness) - metabolic ... #FeedbackLoop #endocrinology ... #pathophysiology
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Hypertension - Renal ... Insufficiency ... PolyarteritisNodosa #Pathophysiology ... Diagnosis #Signs #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
patient has good renal ... Due to neuronal metabolism ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology