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diagnosis toxicology aspirin salicylate signs syndrome bulimianervosa colchicine complications encephalopathy ferrous gitelman hypokalemia iron lacticacidosis mala metformin nephrology neurology pharmacology
Salicylate Toxicity - Diagnosis and Management Consider if: 1) Patient is hot and altered 2) You see tachypnea with
Salicylate Toxicity ... show anion-gap metabolic ... acidosis 4) Presentation ... ingestion/exposure Symptoms ... Alkalosis, High
Colchicine Toxicity Naturally-occurring plant alkaloid [Autumn Crocus and Glory Lilly] 2-24 hrs • Severe GI distress
Colchicine Toxicity ... Naturally-occurring plant alkaloid ... Renal failure • Metabolic ... acidosis • ARDS ... #Toxicology #Symptoms
Metformin Associated Lactic Acidosis (MALA) Pathophysiology of MALA - Metformin interferes with the activity of the
(MALA) Pathophysiology ... also includes symptoms ... of metabolic acidosis ... LacticAcidosis #Toxicity ... Toxicology #Diagnosis #Management
Acute Iron Poisoning There are five classically described phases of toxicity: Gastrointestinal phase (~6 hours post-ingestion) -
post-ingestion) - Symptom ... acidosis (12-48 ... - Anion gap metabolic ... acidosis with both ... Toxicology #Diagnosis #Management
Salicylate Poisoning - Toxicology Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Toxicology Acute toxicity ... mixed respiratory alkalosis ... and metabolic acidosis ... Chronic toxicity ... Pharmacology #Diagnosis #Management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Neurological symptoms ... Medication/Drug toxicity ... , Metabolic disturbance ... Syndrome #diagnosis #management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
alkalosis • Normal ... Hypochloremic metabolic ... Renal tubular acidosis ... diagnosis #nephrology #management ... #pathophysiology
Bulimia Nervosa: Complications GASTROINTESTINAL • Dehydration & inability to digest food -> Constipation • Recurrent vomiting exposes
alkalosis (loss ... abuse may lead to metabolic ... acidosis (loss ... Complications #pathophysiology ... diagnosis #signs #symptoms
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