49 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
(renal potassium ... Hypochloremic metabolic ... Supplement: • Potassium ... #diagnosis #nephrology ... #management #pathophysiology
Emergency management of severe hyperkalemia

#hyperkalemia #management #algorithm #nephrology #Potassium #Treatment
Emergency management ... of severe hyperkalemia ... #hyperkalemia ... #management #algorithm ... #nephrology #Potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Renal Losses: • Metabolic ... Algorithm #causes #potassium ... #low #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... Pressure: - Metabolic ... Hippurate - Metabolic ... #differential #potassium ... #nephrology #low
Hyperkalemia Treatment Options
Stabilize cardiac membrane:
 • IV Calcium (peaks 5-10 minutes)
Decrease potassium concentration:
 • IV Fluids
Shift
Hyperkalemia Treatment ... Fluids Shift potassium ... LouLectures #Hyperkalemia ... #management #potassium ... #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Refeeding Syndrome ... #Hypokalemia ... Algorithm #causes #potassium ... #low #pathophysiology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
• Recent IV potassium ... - Tumor lysis syndrome ... infusions) - Metabolic ... diagnosis #causes #potassium ... #high #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... , Gitelman's syndrome ... #hypokalemia ... algorithm #causes #nephrology ... #potassium
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... • Refeeding syndrome ... MatthewHoMD #Hypokalemia ... Diagnosis #Algorithm #nephrology ... #low #potassium
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #Pathophysiology ... #nephrology #diagnosis