24 results
diagnosis nephrology differential algorithm causes alkalosis hypokalemia metabolic potassium low management urinary urine chronic defects diuresis diuretics encephalopathy excretion fanconi
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome • Urine Chloride • Urine Ca/Cr ratio Dr. Krithika
syndrome from Bartter ... Chloride • Urine ... #syndrome #Bartter ... #Algorithm #nephrology ... #hypokalemia #diagnosis
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
Gitelman Syndrome ... Hypochloremic metabolic ... • Bartter syndrome ... • Pseudo Bartter-Gitelman ... #pathophysiology
Gitelman Syndrome Pathophysiology Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #Syndrome #Pathophysiology
Localization of Renal Tubular Defects Fanconi Syndrome: Proximal tubule Bartter Syndrome: Thick ascending loop of Henle Gitelman Syndrome: Distal
Proximal tubule Bartter ... loop of Henle Gitelman ... #Fanconi #Bartter ... Nephron #Defects #Pathophysiology ... #Nephrology
Hypokalemia - Differential Diagnosis Algorithm Extra-renal Losses: • Normal Acid-Base: Low intake • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... thiazide diuretics, Bartter ... syndrome, Gitelman ... potassium #low #nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm Urine chloride < 20 mmol/l - Chloride responsive (Chloride
Causes of Metabolic ... Decreased BP = Bartter's ... Syndrome, Gitelman's ... Syndrome Dr. ... ThePeanutKidney #Metabolic
Causes of Metabolic Alkalosis - Differential Diagnosis Chloride depletion syndromes • Gastrointestinal losses -
Causes of Metabolic ... Differential Diagnosis Chloride ... furosemide) - Bartter ... Gitelman syndrome ... <2 mmol/L) #Metabolic
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride • Cl- responsive metabolic alkalosis
Algorithm - Urinary Chloride ... suction, Congenital chloride ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
- Urinary Chloride ... diuretic use, Bartter ... syndrome, Gitelman ... syndrome, Hypomagnesemia ... urine #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm Volume Depleted 2° hyperaldosteronism • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Cl-: Diuretics, Bartter ... Syndrome, Gitelman ... #Primary #Metabolic ... Diagnosis #Algorithm #nephrology
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