5 results
Localization of Renal Tubular Defects
Fanconi Syndrome: Proximal tubule
Bartter Syndrome: Thick ascending loop of Henle
Gitelman Syndrome: Distal
Defects Fanconi ... loop of Henle Gitelman ... #Localization #Nephron ... #Defects #Pathophysiology ... #Nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... in the distal tubule ... delivery to distal nephron ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Cerebral Salt Wasting ... vs SIADH - Pathophysiology ... Sodium loss from tubules ... #diagnosis #nephrology ... #hyponatremia #comparison
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... syndrome, Renal tubular ... Rhabdomyolysis Treatment ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... barrier (BBB), and infects ... • Decrease in cerebral ... Treatment: • HAART ... treatment • Cognitive