37 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
DILI and Type of Liver ... Injury #Medications ... #Differential # ... #LiverInjury #Hepatology ... #Pharmacology #
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Medications ... sarahthelyon #Diabetes ... #Medications #pharmacology ... #pathophysiology
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology ... Mechanisms #DOAC #Hematology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... • Indications: ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology ... #indications #dosing
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Toxic: Alcohol, Medication ... GVHD • Toxic: Medication ... #Injury #Differential ... Acute #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injury Differential ... , HSV, VZV • Medications ... #Injury #Differential ... #Diagnosis #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... Most common symptoms ... Diagnosis #Algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... of liver disease ... Drug #induced #Liver ... Idiosyncratic #differential ... gastroenterology #hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Abnormal liver function ... suspicious clinical symptoms ... ; T2DM, type 2 diabetes ... Abnormal #Algorithm #Hepatology ... #Differential #