24 results
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... Associated with DILI ... and Type of Liver ... #LiverInjury #Hepatology ... #Pharmacology #
Drug-Induced Liver Injury - Pathophysiology
Indirect
Idiosyncratic
Direct

BWH Medicine Chiefs @BrighamChiefs

#DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Injury - Pathophysiology ... BrighamChiefs #DILI ... #DrugInduced #Liver ... #hepatology
Topical drug formulations, comparison and considerations

#pharmacology #table #medications #comparison #drugs #treatment #pharmacotherapy #dermatology
, comparison and ... considerations #pharmacology ... #table #medications ... #comparison #drugs ... pharmacotherapy #dermatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Idiosyncratic Drug-induced ... Liver Injury (DILI ... #Drug #induced ... #Liver #Injury # ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Injury (DILI) - ... exposure to HDS, drugs ... non-essential drug ... Diagnosis #Algorithm #hepatology
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Cholangitis #pathophysiology ... #pbc #psc #hepatology ... #comparison
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... (>1000): • DILI ... (Drug-induced liver ... LouLectures #Liver ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... disease, liver ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... 10x ULN), ↑Tbili/Dbili ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... nucleotidase - Liver ... bilirubin (Conjugated/DBili ... impaired uptake (drugs ... Interpretation #diagnosis #hepatology