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diagnosis differential symptoms acromegaly algorithm growthhormone management peds 21hydroxylasedeficiency 21ohd adrenal cah comparison congenitaladrenalhyperplasia excess feedbackloop genetics glftap hyperthyroidism macroadenoma
Acromegaly Caused by over-secretion of growth hormone (GH) from the pituitary gland. The condition is rare
Acromegaly Caused ... growth hormone (GH ... ) from the pituitary ... #Acromegaly #Signs ... Symptoms #Diagnosis #Endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology ... #pituitary
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
adenomas that require treatment ... following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
malignancy Pathophysiology ... • Pituitary ... or refractory cases ... Diagnosis #Management #Endocrinology ... #Treatment #Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... • Other rare causes ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Infographic depicting the main pearls of various types of congenital adrenal hyperplasia for the medical student.
CAH #algorithm #causes ... #pediatrics #CongenitalAdrenalHyperplasia ... diagnosis #comparison #treatment ... #Peds #Endocrinology ... #Adrenal #pathophysiology
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Cushing's Disease • GH ... Panhypopituitarism Treatment ... Diagnosis #Algorithm #endocrinology ... #causes #pediatrics
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
TSH-producing pituitary ... ↑ AST/ALT • Treatment ... hyperthyroidism #causes ... #differential #endocrinology ... #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... • Bilateral signs ... • Infectious causes ... Transverse Myelitis Treatment
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