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diagnosis oncology syndrome treatment abnormal algorithm als amyotrophic apml bandemia biliary causes cbc checklist cholangitis cirrhosis classification coagulation crisis criticalcare
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... but elevated as disease ... bile ducts Differential ... diagnosis #workup #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... • Autoimmune diseases ... #Bandemia #differential ... #CBC #hematology ... #pathophysiology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... incidentally via CBC ... present, symptoms, signs ... von Willebrand disease ... Summary #treatment #hematology
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
exclude other lung disease ... including Ca/Mg/Phos), CBC ... with differential ... monitoring (vital signs ... MyastheniaGravis #Checklist #Management
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... • Severe Liver Disease ... hydration • RBC ... causes #treatment #management ... #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
clinical symptoms/signs ... alcohol-related liver disease ... body mass index; FBC ... Abnormal #Algorithm #Hepatology ... Liver #Enzymes #Differential
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... in improperly folded ... Presentation: - Disease ... conditions listed in differential ... neurology #diagnosis #management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
platelets - WBC ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology ... #oncology #management
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