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diagnosis hematology management chronic cll hodgkins leukemia lymphocytic lymphoma photo poikiloderma rash rheumatology workup abnormal agglutinin algorithm aplastic bandemia cbc
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... repair DNA, as in ... Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... #oncology #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... Neutrophil (Normal) Differential ... likelihood of negative clinical ... #differential # ... #CBC #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Physical Exam/Signs ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
trunk, face or neck ... Episcleritis Signs ... - CBC may also ... Syndrome #diagnosis #dermatology ... #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... the body (the neck ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Shawl sign poikiloderma in Dermatomyositis Poikiloderma in general is a common finding in older individuals with chronic
Shawl sign poikiloderma ... symptoms helps differentiate ... Dermatomyositis #Dermatology ... #Clinical #Photo ... #Neck
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Neck: “dropping ... life-threatening Differential ... Miller Fischer and PCB ... test - Cogan sign ... - Peek sign
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
+Organomegaly+↑RBC ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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