27 results
Babesia spp. on Peripheral Blood Smear Microscopy
 - Multiple small parasites per RBC
 - "maltese cross"
Babesia spp. on Peripheral ... Blood Smear Microscopy ... parasites per RBC ... richdavisphd #Babesia #clinical ... #microscopy #microbiology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Hematuria, Hemoptysis, Peripheral ... ANCA-positive vasculitis ... polyangiitis, Microscopic ... ANCA-negative vasculitis ... Investigations • Labs: CBC
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... disease c-ANCA - Vasculitis ... granulomatosis p-ANCA - Vasculitis ... Microscopic polyangiitis ... diagnosis #table #rheumatology
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
patient with McLeod Syndrome ... expression of Kell RBC ... SpurCells #McLeod #Syndrome ... #Smear #Pathology ... #Microscopy #Clinical
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... DIC is a clinical ... hemolytic #anemia #Hematology ... #Pathology #Smear ... #Microscopy
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
Cryoglobulinemia Vasculitis ... not related to clinical ... Hyperviscosity syndrome ... purpura +++ • Peripheral ... #Diagnosis #Rheumatology
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... recurrent fevers, vasculitis ... • Hematologic ... cells including peripheral
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Glomerulonephritis - Peripheral ... : • Clinical triad ... skin necrosis, peripheral ... - GPA, EGPA, microscopic ... classification #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
PR3-ANCA): • Microscopic ... glomeruli, and peripheral ... • Cogan Syndrome ... Lab Tests: • CBC ... Dx: GPA, EGPA, microscopic