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Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Infiltration: • Hematologic ... and non-hematologic ... deficiency: • B12 ... Algorithm #Causes #Hematology
Methylmalonic Acid and Homocysteine Levels in Vitamin B12 and Folate Deficiency • B12 Deficiency: MMA elevated,
Levels in Vitamin B12 ... Deficiency • B12 ... #Homocysteine #B12 ... VitaminB12 #diagnosis #hematology
Diagnosing Vitamin B12 and/or Folate Deficiency It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin B12 ... serum levels of B12 ... with low normal B12 ... people with low B12 ... Diagnosis #Nutrition #Hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
disease - Vitamin B12 ... Underproduction #Algorithm #hematology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Macrocytic Anemia • 812 ... diagnosis #algorithm #hematology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... Etiology: • Vit B12 ... who don't take B12 ... - Low Vit B12 ... level (< 200 pg
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Low Serum B12 ... - Low Serum B12 ... • Rule out B12 ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
consumption • Vitamin B12 ... Differential #Diagnosis #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Megakaryopoiesis • B12 ... Algorithm #Causes #Hematology
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
crisis • Severe B12 ... differential #diagnosis #hematology
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