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diagnosis differential hematology causes algorithm management pathophysiology signs symptoms physicalexam neurology photo video smear disease iron treatment pediatrics blood bloodsmear
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... intrinsic factor, IF) Clinical ... wt loss • If anemia ... B12 level (< 200 pg ... B12 #Cobalamin #Deficiency
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency ... elliptocytosis, Severe iron deficiency
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... anemia, Thalassemia ... Thalassemia, Iron-deficiency ... Post-splenectomy, Vitamin E deficiency ... cells - G-6-PD deficiency
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Anemia - Underproduction ... Algorithm - Iron deficiency ... anemia - Anemia ... inflammation - Anemia ... and/or folate deficiency
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... and severe iron deficiency ... anemia. ... #Clinical #Path
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron deficiency ... Sideroblastic anemia ... Megaloblastic: Folate deficiency ... , B12 deficiency
Iron Deficiency Anemia vs Anemia of Chronic Disease - Laboratory Testing SUMMARY: - RDW, FEP, serum iron,
Iron Deficiency ... Anemia vs Anemia ... TIBC-specific for iron deficiency ... Bloodman #Iron #Deficiency ... #Anemia #Chronic
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... 80 fL) • Iron Deficiency ... Poisoning • Anemia ... 100 fL) • B12 Deficiency ... • Folate Deficiency
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Megaloblastic Anemia ... Autoimmune hemolytic anemia ... Bite cells: G6PD deficiency ... interpretation #clinical ... #anemia
For an elderly patient with multiple comorbidities it can be challenging to determine if their anemia
determine if their anemia ... secondary to iron deficiency ... as well as anemia ... Diagnosis #Iron #Deficiency ... #Anemia #Algorithm
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