115 results
diagnosis differential hematology causes algorithm iron management workup classification clinical neurology pathophysiology signs symptoms gastroenterology laboratory nephrology vitamin vitaminb12 disease
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... wt loss • If anemia ... B12 level (< 200 pg ... B12 #Cobalamin #Deficiency ... diagnosis #management #nutrition
Risk Factors and Signs of Copper Deficiency Risk Factors: • Gastrointestinal: Previous upper bowel resection/bariatric surgery, Inflammatory
Signs of Copper Deficiency ... Total parenteral nutrition ... /jejunal nutrition ... Haematological: Anaemia ... drkeithsiau #Copper #Deficiency
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
upper limb) • Nutritional ... deficiency Why? ... risk factor for nutritional ... deficiency! ... Management #neurology #nutrition
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... E - Haemolytic anaemia ... Vitamin B12 - Anaemia ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... drkeithsiau #Iron #Deficiency ... differential #diagnosis #anemia ... #nutrition
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • GATA2 deficiency ... • Fanconi’s anemia ... Antibody-mediated hemolysis Nutritional ... B12 • Folate deficiency
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... cancer) #Iron #Deficiency ... diagnosis #causes #nutrition
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: •
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency ... elliptocytosis, Severe iron deficiency
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... anemia, Thalassemia ... Thalassemia, Iron-deficiency ... Post-splenectomy, Vitamin E deficiency ... cells - G-6-PD deficiency
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