13 results
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
differentiating between the diagnosis ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical ... #SJS #skin
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Unstable hemoglobin disorders ... iron deficiency anemia ... RBC: Hemoglobin SS ... RBC #Morphology #differential ... #diagnosis #hematology
Skin Ulcers by Etiology - Differential Diagnosis Algorithm
Physical:
 • Trauma
 • Pressure
 • Radiation
Vascular:
 • Arterial
Skin Ulcers by Etiology ... - Differential ... • Factitious disorder ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... purple, hemorrhagic skin ... - Hemolytic anemia ... #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... diverse genotypes): SS ... Consider RBC membrane disorder
Christmas Tree Rash of Pityriasis rosea
 - small oval scaling patches
 - Christmas tree pattern
 -
parallel to lines of skin ... palms/soles - Differential ... diagnosis: secondary ... #dermatology #photo ... #PhysicalExam
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... anemia • Cold ... younger pts) Differential ... #hematology #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Vasculitis - Collagen disorders ... cryoglobulins • Skin ... #Causes #dermatology ... #physicalexam
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... phenomenon CLL Diagnosis ... lymphoproliferative disorders ... • Neutropenia, anemia
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... just beneath the skin ... Neutropenia • Platelet Disorders ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis