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hematology blood product reactions syndrome algorithm anemia apml atlas bloodcell classification differentiation dress hemolytic hodgkins lymphoma microscopy monoclonal morphology nomenclature
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential ... Diagnosis Algorithm ... diverse genotypes): SS ... #Anemia #Differential ... #workup #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
extensive skin rash ... Resolution > 15 days Differentials ... drug reaction • SJS ... DRESS #Syndrome #dermatology ... #diagnosis #management
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... RBC: Hemoglobin SS ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Febrile Non-Hemolytic ... Hemolysis on labs ... maculopapular rash ... #Transfusion #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
opacities • Diagnosis ... initiation • Differential ... Diagnosis: Infection ... #management #hematology ... #oncology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Hemolysis on labs ... maculopapular rash ... #Transfusions #diagnosis ... #management #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
nodosum • Immune hemolytic ... lymph node biopsy (diagnostic ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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