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diagnosis hematology leukemia management workup algorithm atlas bloodcell calculation classification common cvid erythematosus hemeonc hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology index
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... - infiltrates (anemia ... (Chronic Lymphocytic ... lymphoid organs When Cancer ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Leukemia - Summary Cancer ... Lymphadenopathy • Fevers ... • Neutropenia, anemia ... #Chronic #Lymphocytic
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... ) B symptoms → fevers ... 5) Symptoms of anemia ... #Chronic #Lymphocytic ... #Leukemia #oncology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... RBC: Hemoglobin SS ... myeloma Rouleaux: Chronic ... RBC #Morphology #differential ... #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
deficiencies: Chronic ... infiltration (e.g. cancer ... defects (e.g. sickle cell ... Production #Index #hematology ... #anemia #differential
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Consider sickle cell ... diverse genotypes): SS ... bartonella (oroya fever
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Weight loss • Anemia ... Immune hemolytic anemia ... Immunohistochemical studies (to differentiate ... #oncology #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Lymphoma or other cancers ... gastric and breast cancer ... Granulomatous lymphocytic ... autoimmune hemolytic anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
count (anemia) ... Marrow Failure • Chronic ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Immunocompromised status • Chronic ... encounters due to NTM: Chronic ... disease, alcohol, cancer ... Bone Marrow - Anemia ... NTM #Infections #differential
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