19 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... - Pel-Ebstein fever ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
immunophenotype Clinical ... ) B symptoms → fevers ... #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia, Chronic ... RBC: Hemoglobin SS ... myeloma Rouleaux: Chronic ... RBC #Morphology #differential ... #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Consider sickle cell ... diverse genotypes): SS ... bartonella (oroya fever ... Algorithm #workup #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Fever >38.5 2. ... Resolution > 15 days Differentials ... drug reaction • SJS ... DRESS #Syndrome #dermatology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Induce blast cell ... Subacute-Acute: • Common: fever ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
All oysters at Chesapeake ... Rapid onset of fever ... 🦪 🦀 sepsis: chronic ... rash #cellulitis #dermatology ... #legs #clinical
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
lymphoid malignancy (CLL ... Viral Infection Clinical ... younger pts) Differential ... Symptoms: High fevers ... hemolytic #anemia #hematology