17 results
Anemia - Underproduction Diagnostic Algorithm
 - Iron deficiency anemia
 - Anemia of chronic inflammation
 - Anemia
Diagnostic Algorithm ... - Iron deficiency ... Vitamin B12 and/or folate ... #differential # ... workup
Approach to Hypoproliferative Macrocytic Anemia

 • 812, Folate Deficiency
 • MDS+
 • Hypothyroid
 • Liver Disease
• 812, Folate ... Deficiency • ... #differential # ... diagnosis #algorithm ... #hematology #workup
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
- Differential ... Diagnosis Framework ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Megaloblastic: Folate
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Bleeding • Hemolysis ... • Folate Deficiency ... #Diagnosis #Algorithm
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... - Drugs (Beta lactam ... G6PD deficiency) ... Extravascular #Causes #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... Diagnosis Algorithm ... #Anemia #Differential ... #workup #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... Diagnosis Congenital ... • Fanconi’s anemia ... Antibody-mediated hemolysis ... Vitamin B12 • Folate
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... disease #LDH #Lactate ... #diagnosis #Laboratory
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Vitamin B12 or Folate ... Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... RBC #Morphology #differential ... #diagnosis #hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
Hemorrhage or hemolysis ... of the initial work-up ... but undiagnosed, folate ... #Diagnosis #Macrocytosis ... #VitaminB12 #Folate