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diagnosis symptoms hematology treatment antinxp2 antinxp2dm behcet cushings deficiency dermatology dermatomyositis differential edema erythematosus facial hemophagocytic hlh hypercortisolism hypomagnesemia insufficiency
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... disease (30%): ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... WBC >100k, + lab signs ... worrisome EKG features ... TLS #diagnosis #management ... #hematology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
Cushing's Syndrome ... Diagnosis and Clinical Features ... the abdomen for adrenal ... Hypercortisolism #Diagnosis #signs ... #symptoms #endocrinology
Facial Swelling - Differential Diagnosis Framework for Facial Edema Infectious: • Dental abscess • Ludwig's angina • Vincent's angina • Cellulitis •
• Pott's puffy tumor ... Adult-onset Still's disease ... Subcutaneous emphysema Renal ... : • Morbihan disease ... Differential #Diagnosis #PhysicalExam
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Diagnosis and Management ... or metastatic disease ... , infiltrative diseases ... hypophysitis, Sheehan's syndrome ... #Endocrinology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... interferon alfa, or tumor ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... Diagnosis: HLH signs ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... ducts Clinical Features ... Distal (Type I) renal ... #Rheumatology # ... Diagnosis #Management
Clinical Feature of Hypomagnesemia and Magnesium Deficiency • Electrolyte Disturbance: Hypokalemia, Hypocalcemia • Neuromuscular and central
Clinical Feature ... fasciculations, tremors ... Atherosclerotic vascular disease ... Chronic fatigue syndrome ... symptoms #Treatment #management
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
chest (in a V-sign ... and Biological Features ... had more severe disease ... Dermatomyositis #diagnosis #management ... #rheumatology #
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