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Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... (DILI) - Stepwise ... involvement, Kidney injury ... dates) Potential pitfalls ... DrugInduced #Liver #Injury
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Drug-induced Liver Injury ... (DILI) DILI ... dose dependent injury ... • Cholestatic DILI ... induced #Liver #Injury
Drugs and Classes Associated with DILI and Type of Liver Injury #Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Associated with DILI ... Type of Liver Injury ... Pharmacology #Causes #DILI
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 Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver Injury ... BrighamChiefs #DILI ... DrugInduced #Liver #Injury
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... of Acute Liver Injury ... • Iatrogenic: DILI ... Unconjugated Bili ... > 90% of Total Bili
Amiodarone-Induced Lung Iniurv (AILI) - Timeline Hours to days (peri-procedurally): ARDS Days to months: DAH Weeks: Eosinophilic pneumonia Weeks to
Amiodarone-Induced Lung Iniurv ... (AILI) - Timeline ... Induced #LungIniurv #AILI
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
(>1000): • DILI ... Drug-induced liver injury
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Drug-Induced Liver Injury ... (DILI) Viral Hepatitis
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
abnormality vs bone Bili ... Hepatocellular injury ... 2: Cholestatic injury
Anterior Cruciate Ligament Injury seen with positive Anterior Drawer Test #Anterior #Cruciate #Ligament #ACL #Injury #Drawer #Test
Cruciate Ligament Injury ... Ligament #ACL #Injury ... physicalexam #clinical #video
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