358 results
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Menorrhagia • GI bleeding ... children) • Platelets ... only for severe bleeding ... extremely low platelet
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... Defects #comparison #table ... #differential #
Thresholds for Transfusion of Platelets in Adults
Major surgery or invasive procedure, no active bleeding - 
≤
Transfusion of Platelets ... procedure, no active bleeding ... Surgery with active bleeding ... 100 (rarely) Stable ... #Management #Platelets
Indications for Transfusion
Packed RBCs
 • Hgb <7 g/dL or hematocrit <21% in a patient with uncompromised
hemoglobinopathy Platelets ... • < 30,000 and bleeding ... postoperative bleeding ... < 100,000 and bleeding ... Platelet transfusions
Bleeding and Bruising - Differential Diagnosis Algorithm
 • Vascular System Defect - Congenital vs Acquired
 •
Bleeding and Bruising ... - Differential ... vs Acquired • Platelet ... vs Acquired #Bleeding ... #Bruising #Differential
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... Thrombocytosis #Differential ... Diagnosis #causes #Platelets
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... count and platelet ... 1 or Type 3) — differentiate ... • Platelet flow ... hematology #hemepath #differential
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
in Pregnancy - Differential ... Creatinine - Platelets ... AKI #Pregnancy #Differential ... Diagnosis #Causes #table
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... B-symptoms, bruising/bleeding ... anemia, ↑ MCV, ↑/↓ platelets ... #Leukocytosis #Differential
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... Hct < .005) Platelet ... pheresis - Platelets ... Hematology #Management #Table