3969 results
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
osmolarity If cause ... fragmentocytes, LDH, platelets ... Differential #Diagnosis #nephrology ... #causes
Pseudohyperkalemia vs Reverse Hyperkalemia

Pseudohyperkalemia and reverse pseudohyperkalemia are both conditions where potassium levels appear falsely elevated.

Pseudohyperkalemia:
This
cells (usually platelets ... Causes: • Thrombocytosis ... (high platelet ... Causes: • Seen ... Hyperkalemia #Potassium #Nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Reticulocyte count/platelet ... infections are common causes ... nephrotic #nephritic #nephrology
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
Inherited Qualitative Platelet ... Single isolated platelets ... without platelet ... failure Grey Platelet ... • Absence of platelet
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis Platelet ... Differential #Diagnosis #causes ... #Platelets #hematology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Reticulocyte count/platelet ... infections are common causes ... initial #testing #nephrology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... ristocetin • Normal platelet ... count and platelet ... • Platelet flow ... Usually normal platelet
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
children) • Platelets ... extremely low platelet
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... History: - Prior platelet ... patients if the cause ... Thrombocytopenia #Platelet ... Differential #Diagnosis #Causes
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
WBC and platelets ... Hct 60% Platelet ... concentrate - Platelets ... Hct < .005) Platelet ... pheresis - Platelets