31 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Ivermectin. Old anti-parasitic agent making a comeback with recent headlines from in-vitro study that showed antiviral
Old anti-parasitic ... Pandemic #Outbreak #InfectiousDiseases ... EmergencyMedicine #Pharmacology ... Virus #Antiviral #Management
Mild Acne Treatment - Comedones (black/whiteheads), +/- few pustules 
1. Benzoyl Peroxide (BP) 
2. Topical Retinoid
Mild Acne Treatment ... few pustules 1. ... First line pharmacologic ... #Management #Comedones ... #Pharmacology #
Adjuvant therapies in critical care: steroids to treat infectious diseases
 - Severe Community Acquired Pneumonia
jirovecii pneumonia, id ... Corticosteroids #Adjuvant #InfectiousDiseases ... #Infections #Pharmacology ... #Management #Treatment
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
Consult ID if needed ... ampicillin #management ... #infectiousdisease ... #antibiogram #pharmacology
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
Croup Management ... children with mild ... 2 puffs < 1 ... SarahFoohey #Croup #Management ... Epinephrine #dosing #pharmacology
Stress Ulcer Prophylaxis

Stress ulcerations are common in ICU patients and may lead to hemorrhage if not
Critically ill patients ... hospitalization) • Pathophysiology ... Presentation • Management ... #criticalcare #pharmacology ... #management
Vasopressors and Inotropes - Pharmacology Summary
Vasopressors
Phenylephrine (alpha-1)
 • Increases BP, SVR
 • Risk of reflex bradycardia
and Inotropes - Pharmacology ... Levophed, alpha-1 ... dilation • beta /mild ... Vasopressors #Inotropes #Pharmacology ... #Summary #management
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
PATHOPHYSIOLOGY: ... Pyrogen (TNF, IL ... -1, IFN, IL-6): ... Rigors #Bacteremia #Pathophysiology ... #InfectiousDiseases
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
eliminate about 1/ ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management