15 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Digoxin Pharmacology ... and Pathophysiology ... 1) Na/K ATPase ... CaitEKulig #Digoxin #Pharmacology ... #Pathophysiology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Effects: Edema (mild ... as necessary at 1- ... magnesium, and calcium ... level teaspoons) 1- ... #medications #pharmacology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
drug-dependent, 4:1 ... to 1:1 F:M • Clinical ... thiazidic, PPI, ACE, calcium-b ... Prognosis: Usually mild ... comparison #table #rheumatology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Classification: CLASS 1 ... repolarization) CLASS 4 - Calcium ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... precipitates with calcium ... to Manifest: 1. ... Gout #Comparison #rheumatology
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Classification: CLASS 1 ... repolarization) CLASS 4 - Calcium ... Antiarrhythmics #Pharmacology ... Classification #Classes #pathophysiology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... • Interstitial Pneumonitis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology