14 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
synthesis, e.g., IL ... -1, IL-2 Muromonab-CD3 ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm
Idiopathic Interstitial Pneumonia
 • (UIP) Usual Interstitial Pneumonia
this should be 1° ... Hypersensitivity Pneumonia - Immunologic ... Chronic Radiation Pneumonitis ... Lung #Diseases #ILD
Inflammatory mechanism of asthma. 
Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
cytokines such as IL ... -5 and IL-1 3, which ... #asthma #pathophysiology ... #inflammatory #immunology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... drug-dependent) • Immunologic ... Prognosis: Usually mild ... Cytopenia: Common • Immunologic ... comparison #table #rheumatology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... #Pathophysiology
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
hypersensitivity/immunologic ... including: 1. ... : Interstitial pneumonitis ... Exclusion of other ILDs ... : Interstitial pneumonitis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... arthritic flare. 1. ... to Manifest: 1. ... Gout #Comparison #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... • Interstitial Pneumonitis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
drug-dependent, 4:1 ... to 1:1 F:M • Clinical ... drug-dependent) • Immunologic ... Prognosis: Usually mild ... DrugInduced #Lupus #DIL #rheumatology