12 results
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
5 of the below criteria ... should be major: 1. ... Minor criteria include ... Treatment - Mild ... AOSD #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL ... -1 and IL-6, leading ... Histopathologic criteria ... Diagnosis #Management #Hematology ... #Rheumatology
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... heat stress • Criteria ... Multi-system illness: 1. ... temperatures • Criteria ... Findings: - Mild
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
at > 17 years old ... than females (4:1) ... BehavioralDisorder #Pathophysiology ... signs #psychiatry #criteria
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... disease states Pathophysiology ... arthritic flare. 1. ... to Manifest: 1. ... Gout #Comparison #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... CNS • Headache, mild ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... varying degrees of: 1. ... Diagnostic Criteria ... - Pleocytosis: Mild
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... Antinuclear antibodies ≥ 1: ... • Interstitial Pneumonitis ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
months, with >1 ... individual is >18 years old ... , criteria must ... in childhood (> 1 ... BehavioralDisorder #Pathophysiology