32 results
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Action Diuretics 1) ... Adenosine #Nephron #Pathophysiology ... Sites #Action #nephrology ... #pharmacology
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
., IL-1, IL-2 Muromonab-CD3 ... Basiliximab - IL ... Suppression of IL ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
manifestations Stage 1. ... • Heralded by neurologic ... joints (knees), 1- ... Remitting, chronic • Neurologic ... diagnosis #signs #symptoms
Croup Management - Epinephrine Dosing
Use steroids appropriately, as needed
In older children with mild symptoms, may consider
children with mild ... symptoms, may consider ... 2 puffs < 1 ... 4 puffs ≥ 1 ... Epinephrine #dosing #pharmacology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Lamotrigine • Mild ... , asthenia • Neurologic ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Adult Vancomycin Guidelines
The information below provides general dosing guidelines for vancomycin. A maintenance regimen of 15-20
AUC: MIC ratio.1 ... reference source and nephrology ... complex critically ill ... #Management #Pharmacology
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... at > 17 years old ... 2 settings - Symptoms ... than females (4:1) ... BehavioralDisorder #Pathophysiology
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Antibodies: Anti-Jo-1, ... Demographics: - F:M, 2:1 ... dehydrogenase (LD ... PM #Diagnosis #Pathophysiology ... #Signs #Symptoms
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Epidemiology: • 1- ... Guillain-Barre Pathophysiology ... • Weakness: mild ... main variants: (1) ... management #treatment #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
• Incidence: 1 ... can vary from mild ... than one after symptom ... the underlying pathophysiology ... diagnosis #management #neurology