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management sle differential disease erythematosus hematology systemic activation adult aosd calcium comparison cppd deposition dil drugs hemeonc hemophagocytic hlh lymphohistiocytosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... life-threatening • Treatment ... Lupusreference #druginduced ... #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
-1 and IL-6, leading ... Histopathologic criteria ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
- Yamaguchi criteria ... should be major: 1. ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... pneumonitis • ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... #Rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... #diagnosis #treatment
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Induced Systemic Lupus ... year of treatment ... Lupusreference #DrugInduced ... #differential #diagnosis ... #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... varying degrees of: 1. ... Criteria: • Sensory ... - Pleocytosis: Mild ... Transverse Myelitis Treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... Pathophysiology ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
including systemic lupus ... cell lymphoma Pathophysiology ... Histopathological Diagnoses ... Hypoalbuminemia Treatment ... #management #rheumatology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Disease (CPPD) Pathophysiology ... trauma (> 65 years old ... disease states 1. ... Acute Pseudogout: Treatment ... Deposition #Disease #Rheumatology
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