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diagnosis table differential management cppd dermatology lupus pulmonary sle antibodies antimda5 antimda5dm antinxp2 antinxp2dm autoantibodies autoimmune calcium clinical cold connectivetissuediseases
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
DM/PM : dermatomyositis ... ConnectiveTissueDiseases #ILD ... #Differential #Comparison ... Table #Pulmonary #Rheumatology ... #Associations
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Associations ANA ... Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... Autoantibodies #Associations ... #table #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
severity of the disease ... and ILD • Liver ... frequently described Association ... Phenotype 1 ... #rheumatology #
On the left some diseases with a nodular pattern. 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary
the left some diseases ... nodular pattern. 1. ... Hypersensitivity pneumonitis ... Hypersensitivity pneumonitis ... #Differential #Comparison
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
Causes and clinical associations ... - 1. ... of symptoms - 1- ... Urticaria #diagnosis #rheumatology ... #comparison #table
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... Non-autoimmune rheumatologic ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1,
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
had more severe disease ... • Myoglobin Association ... : • ILD was diagnosed ... Prednisone at 1 ... diagnosis #management #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... resolves after > 1 ... cartilage triggers a mild ... #Degenerative #Comparison ... JointPain #Diagnosis #pathophysiology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... • Underlying disease ... states Pathophysiology ... #CPPD #Gout #Comparison ... #rheumatology #
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