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diagnosis differential management associations lupus pulmonary sle antinxp2 antinxp2dm autoantibodies autoimmune clinical connectivetissuediseases cppd ctchest ctild dermatology diseases druginduced erythematosus
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
DM/PM : dermatomyositis ... ConnectiveTissueDiseases #ILD ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... #diagnosis #table ... #rheumatology # ... antibodies
On the left some diseases with a nodular pattern. 1. Hypersensitivity pneumonitis: ill defined centrilobular nodules. 2. Miliary
the left some diseases ... nodular pattern. 1. ... Hypersensitivity pneumonitis ... #Differential #Comparison ... #Table #RadiologyAssistant
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... SCL-70, RNP antibodies
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Prognosis: Usually mild ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #table #rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... Ab • Anti-Jo-1 ... enzymes • Anti-Jo-1 ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... had more severe disease ... : • ILD was diagnosed ... Prednisone at 1 ... diagnosis #management #rheumatology
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
trauma (> 65 years old ... • Underlying disease ... states Pathophysiology ... #CPPD #Gout #Comparison ... #rheumatology #
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
dysfunction. 1. ... ▪ Autoimmune diseases ... Pathophysiology ... inhibitors, anti-IFN-γ antibodies ... Diagnosis #Management #Hematology
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