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diagnosis differential infectiousdiseases lupus sle abscess antinxp2 antinxp2dm associations autoantibodies autoimmune calcium causes coccidioidomycosis comparison cppd deposition dermatology diseases druginduced
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Drug-induced SLE Anti-Jo-1 ... Polymyositis / Dermatomyositis ... #diagnosis #table ... #rheumatology # ... antibodies
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, dermatomyositis ... • Acute lupus pneumonitis ... • ANA titers > 1: ... Ro/La, anti-Jo-1, ... SCL-70, RNP antibodies
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Diagnosis and Management ... Lung Abscess Pathophysiology ... : 1. ... Pneumonitis 3. ... Lung Abscess Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Epidemiology: • F > M: 9:1 ... ≥ 1:320 • Cytopenia ... • Interstitial Pneumonitis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Anti-MDA5 (RP-ILD ... ), dermato-rheumatologic ... Ab • Anti-Jo-1 ... enzymes • Anti-Jo-1 ... Myositis #Myopathy #rheumatology
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
• Antibodies targeting ... had more severe disease ... : • ILD was diagnosed ... #diagnosis #management ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Prognosis: Usually mild ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... varying degrees of: 1. ... - Pleocytosis: Mild ... Antiamphiphysin antibodies ... Myelitis #diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
pulmonary symptoms • Rheumatologic ... clinical forms: 1) ... for Blastomyces antibodies ... Aspergillosis Pathophysiology ... Fungal #Diagnosis #Management
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
Diagnosis and Management ... for IgM and IgG antibodies ... titer greater than 1: ... patients with mild ... Fever #Diagnosis #Management
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